Publications

2021

HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain

eLife (2021)

Edgar E Boczek, Julius Fürsch, Marie Laura Niedermeier, Louise Jawerth, Marcus Jahnel, Martine Ruer-Gruß, Kai-Michael Kammer, Peter Heid, Laura Mediani, Jie Wang, Xiao Yan, Andrej Pozniakovski, Ina Poser, Daniel Mateju, Lars Hubatsch, Serena Carra, Simon Alberti, Anthony A Hyman, Florian Stengel

Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo

Biophysical Journal (2021)

SoRi Jang, Zhao Xuan, Ross C Lagoy, Louise M Jawerth, Ian J Gonzalez, Milind Singh, Shavanie Prashad, Hee Soo Kim, Avinash Patel, Dirk R Albrecht, Anthony A Hyman, Daniel A Colón-Ramos

Quantitative theory for the diffusive dynamics of liquid condensates

eLife (2021)

Lars Hubatsch, Louise M. Jawerth, Celina Love, J. Bauermann, Dora Tang, Stefano Bo, Anthony Hyman, Chrisoph Weber

2020

Protein condensates as aging Maxwell fluids

Science (Dec. 2020)

L. M. Jawerth, E. Fischer-Friedrich, Saha Suropriya, J. Wang, T. Franzmann, X. Zhang, J. Sachweh, M. Ruer, M. Ijavi, S. Saha, J. Mahamid, A. Hyman, F. Jülicher

In this paper, we quantify the material properties of protein droplets over time. It is one of the first quantitative studies on how the viscoelastic properties of these materials change over time. We find that dynamics of the droplets slow over time.

Quantitative phase microscopy enables precise and efficient determination of biomolecular condensate composition

bioRxiv (2020)

Patrick M McCall, Kyoohyun Kim, Anatol W Fritsch, JM Iglesias-Artola, LM Jawerth, Jie Wang, Martine Ruer, J Peychl, Andrey Poznyakovskiy, Jochen Guck, Simon Alberti, Anthony A Hyman, Jan Brugués

PRE-2018

Salt-dependent rheology and surface tension of protein condensates using optical traps

Physical Review Letters (2018)

Louise M Jawerth, Mahdiye Ijavi, Martine Ruer, Shambaditya Saha, Marcus Jahnel, Anthony A Hyman, Frank Jülicher, Elisabeth Fischer-Friedrich

Physical limits to biomechanical sensing in disordered fibre networks

Nature communications (2017)

Farzan Beroz, Louise M Jawerth, Stefan Münster, David A Weitz, Chase P Broedersz, Ned S Wingreen

Tracking the structural deformation of a sheared biopolymer network

Functional Analysis, Harmonic Analysis, and Image Processing: A Collection of Papers in Honor of Björn Jawerth (2017)

Louise M Jawerth, David A Weitz

Polar positioning of phase-separated liquid compartments in cells regulated by an mRNA competition mechanism

Cell (2016)

Shambaditya Saha, Christoph A Weber, Marco Nousch, Omar Adame-Arana, Carsten Hoege, Marco Y Hein, Erin Osborne-Nishimura, Julia Mahamid, Marcus Jahnel, Louise Jawerth, Andrej Pozniakovski, Christian R Eckmann, Frank Jülicher, Anthony A Hyman

A liquid-to-solid phase transition of the ALS protein FUS accelerated by disease mutation

Cell (2015)

Avinash Patel*, Hyun O Lee*, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus M Franzmann, Andrej Pozniakovski, Ina Poser, Nicola Maghelli, Loic A Royer, Martin Weigert, Eugene W Myers, Stephan Grill, David Drechsel, Anthony A Hyman, Simon Alberti

Stress controls the mechanics of collagen networks

Proceedings of the National Academy of Sciences (2015)

Albert James* Licup, Stefan* Münster, Abhinav Sharma, Michael Sheinman, Louise M Jawerth, Ben Fabry, David A Weitz, Fred C MacKintosh

Strain history dependence of the nonlinear stress response of fibrin and collagen networks

Proceedings of the National Academy of Sciences (2013)

Stefan Münster, Louise M Jawerth, Beverly A Leslie, Jeffrey I Weitz, Ben Fabry, David A Weitz

Structure and mechanics of fibrin clots formed under mechanical perturbation

Journal of Thrombosis and Haemostasis (2013)

S Münster, LM Jawerth, B Fabry, DA Weitz

Finite-strain, finite-size mechanics of rigidly cross-linked biopolymer networks

Soft Matter (2013)

Stefan B Lindström, Artem Kulachenko, Louise M Jawerth, David A Vader

A blind spot in confocal reflection microscopy: the dependence of fiber brightness on fiber orientation in imaging biopolymer networks

Biophysical journal (2010)

Louise M Jawerth, Stefan Münster, David A Vader, Ben Fabry, David A Weitz